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Neurodegenerative Disorders >> Autonomic Nervous System Failure
The autonomic nervous system is the body’s “automatic nervous system,” responsible for involuntary, unconscious, automatic changes in the body’s organs such as the heart. When one or more parts of the autonomic nervous system fail, conditions such as lightheadedness or fainting when standing up, a fall in blood pressure when standing or after eating, fatigue, dry mouth and dry eyes, inability to sweat, constipation, and urinary problems may occur.
General Study Procedures:
The research studies listed below are currently open for enrollment for adult subjects. They may involve evaluation of autonomic function, using physiological, neuropharmacologic, neurochemical, and neuroimaging approaches to identify lesion types and sites in chronic autonomic failure. There is also one clinical trial of experimental treatment for particular autonomic failure syndromes. Please see the links for the procedures and eligibility criteria for specific studies. There is no cost for participation or for any tests associated with the research.
Studies Actively Recruiting Patients:
Evaluation of Primary Chronic Autonomic Failure
For more information about participating in these studies, please contact :
For protocol 03-N-0004
Sandra Pechnik, R.N.
Bldg. 10, CRC 7-5653
10 Center Drive, MSC1620
Bethesda, MD 20892-1620
Patient Recruitment and Public Liaison Office toll-free at:
For more information on
Autonomic Nervous System Failure
NINDS AT THE CLINICAL CENTER