National Clinical Center
Search: 
 
Home Disorders Clinical Center
 

Movement Disorders
Neuroimmunology
Stroke and Vascular Disorders
Epilepsy
Memory Disorders & Dementia
Familial & Hereditary Disorders
Neurosurgical Disorders & Brain Tumors
Neurodegenerative Disorders
Brain Injury
Neuromuscular Disorders
Neurological Disorders of Children

Neuroimmunology >> Multiple Sclerosis

Disease Description:
Multiple sclerosis (MS) is a chronic disorder affecting movement, sensation, and bodily functions. It is caused by destroying the layer (called myelin) of cells surrounding neurons in the brain and spinal cord. Myelin helps electrical signals pass quickly and smoothly between the brain and the rest of the body. When the myelin is destroyed, nerve messages are sent more slowly and less efficiently. The symptoms of MS occur when the brain and spinal cord nerves no longer communicate properly with other parts of the body. MS causes a wide variety of symptoms and can affect vision, balance, strength, sensation, coordination, and bodily functions.

General Study Procedures:
The research studies listed below are currently open for enrollment for adult subjects. These may involve primary screening and neuroimaging procedures; administering various combinations of drugs, and testing cognitive function. Please see the links for the procedures and eligibility criteria for specific studies. There is no cost for participation or for any tests associated with the research.

Studies Actively Recruiting Patients:
89-N-0045: Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
09-N-0032: Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System
09-N-0197: Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients With Primary Progressive Multiple Sclerosis
10-N-0212: Double Blind Combination of Rituximab by Intravenous and Intrathecal Injection Versus Placebo in Patients With Low-Inflammatory Secondary Progressive Multiple Sclerosis (RIVITaLISe)
13-N-0088: Idebenone for Primary Progressive Multiple Sclerosis
00-N-0043: Study of Inherited Neurological Disorders
13-N-0104: Natural history of optic neuritis

For more information about participating in these studies, please contact :
For protocol 13-N-0104 or 89-N-0045 or 09-N-0197 or 09-N-0032
Joan Ohayon, CRNP
NINDS, NIB
Bldg. 10, Room 5C101
10 Center Drive, MSC 1400
Bethesda, MD 20892-1400
Tel: 301-496-0064
Email: ohayonj@ninds.nih.gov

For protocol 10-N-0212
Kaylan Fenton
Bldg. 10, Room 5C101
10 Center Dr., MSC 1400
Bethesda, MD 20892-1400
Tel: 301-496-0064
Email: fentonk@ninds.nih.gov

For protocol 00-N-0043
Patient Recruitment and Public Liaison Office
NIH, DHHS
Bldg. 61, #10 Cloister Court
Bethesda, MD 20892-4754
Tel: 800-411-1222; 866-411-1010 (TTY)
Email: prpl@mail.cc.nih.gov

For protocol 13-N-0088
Jenifer Dwyer, R.N.

Tel: 301-496-0064
Email: jdwyer@ninds.nih.gov

or
Patient Recruitment and Public Liaison Office toll-free at:
1-800-411-1222
TTY: 1-866-411-1010

For more information on Multiple Sclerosis:


NINDS HOME ACCESSIBILITY INFORMATION NINDS AT THE CLINICAL CENTER PRIVACY STATEMENT RECRUITMENT CONTACT
U.S. Department of Health & Human Services National Institutes of Health National Institute of Neurological Disorders and Stroke The U.S. Government's Official Web Portal