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Movement Disorders >> Dystonia
Dystonia is a condition in which muscles contract involuntarily. It often leads to twisted postures of the head, arms or legs. There are different kinds of dystonia. Some affect the entire body while some affect only one part of the body. In task-specific dystonia, the involuntary contractions occur only when carrying out particular tasks, such as writing (writer’s cramp) or playing a musical instrument (musician’s cramp). In blepharospasm, uncontrollable blinking of the eyelids is the most common. The causes of dystonia are not well understood. The research focuses on finding the causes and better forms of experimental treatment.
General Study Procedures:
The research studies listed below are currently open for enrollment for adult subjects. They may involve physiological studies to measure the activity in the brain and the muscles; imaging studies such as MRI of the brain while carrying out movements; PET studies of neurotransmitters; and experimental treatment studies with retraining techniques or injections of botulinum toxin. Please see the links below for the procedures and eligibility criteria for specific studies. There is no cost for participation or for any tests associated with the research.
Studies Actively Recruiting Patients:
Movement-Related Brain Networks Involved in Hand Dystonia
For more information about participating in these studies, please contact :
For protocol 05-N-0228
Elaine Considine, R.N.
DIR, MNB, NINDS
Bldg. 10, Room 7D36A
10 Center Drive, MSC 1428
Bethesda, MD 20892-1428
Tel: 301 435 8518
Patient Recruitment and Public Liaison Office toll-free at:
For more information on
NINDS AT THE CLINICAL CENTER